DVL1

Segment polarity protein dishevelled homolog DVL-1 is a protein in humans that is encoded by DVL1 gene. Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

DVL1 Proteins

DVL1 Proteins for Mus musculus (Mouse)

DVL1 Proteins for Homo sapiens (Human)

DVL1 Proteins for Pan troglodytes (Chimpanzee)

DVL1 Proteins for Rattus norvegicus (Rat)

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