DVL1

Segment polarity protein dishevelled homolog DVL-1 is a protein in humans that is encoded by DVL1 gene. Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

The following DVL1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

DVL1 Proteins

DVL1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP007284MO CSB-EP007284MO CSB-BP007284MO CSB-MP007284MO CSB-EP007284MO-B	Recombinant Mouse Segment polarity protein dishevelled homolog DVL-1 (Dvl1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DVL1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP007284HU CSB-BP007284HU CSB-MP007284HU CSB-EP007284HU-B	Recombinant Human Segment polarity protein dishevelled homolog DVL-1 (DVL1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DVL1 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP692214EQV CSB-EP692214EQV CSB-BP692214EQV CSB-MP692214EQV CSB-EP692214EQV-B	Recombinant Pan troglodytes Segment polarity protein dishevelled homolog DVL-1 (DVL1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DVL1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP895301RA CSB-EP895301RA CSB-BP895301RA CSB-MP895301RA CSB-EP895301RA-B	Recombinant Rat Segment polarity protein dishevelled homolog DVL-1 (Dvl1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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