ERCC6 Research Reagents

DNA excision repair protein ERCC-6 is a protein in humans that is encoded by ERCC6 gene. Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.

The following ERCC6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ERCC6 Antibodies

ERCC6 Antibodies for Homo sapiens (Human)

ERCC6 Proteins

ERCC6 Proteins for Homo sapiens (Human)

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