ETS2

Ets2, a member of the ETS family of transcription factors, is encoded by the ETS2 gene and expressed across various cell types. It plays a role in cell proliferation, differentiation, migration, and apoptosis by binding to GGAA/T motifs in DNA, thereby regulating the transcription of downstream genes. Ets2's interaction with signaling pathways such as MAPK and PI3K/AKT is crucial for its wide-ranging biological impact, including embryonic development, tissue regeneration, immune response, and tumorigenesis.