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Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).
The following EYA4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
EYA4 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA007909LA01HU | EYA4 Antibody |
Human | ELISA, IHC, IF |
| CSB-PA007909LB01HU | EYA4 Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA007909LC01HU | EYA4 Antibody, FITC conjugated |
Human | |
| CSB-PA007909LD01HU | EYA4 Antibody, Biotin conjugated |
Human | ELISA |
EYA4 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP007909HU CSB-EP007909HU CSB-BP007909HU CSB-MP007909HU CSB-EP007909HU-B |
Recombinant Human Eyes absent homolog 4 (EYA4) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EYA4 Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP897045TKY CSB-EP897045TKY CSB-BP897045TKY CSB-MP897045TKY CSB-EP897045TKY-B |
Recombinant Takifugu rubripes Eyes absent homolog 4 (eya4) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
