Tumor necrosis factor receptor superfamily member 6 is a protein in humans that is encoded by FAS gene. Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

FAS Antibodies

FAS Antibodies for Homo sapiens (Human)

FAS Proteins

FAS Proteins for Homo sapiens (Human)

FAS Proteins for Rattus norvegicus (Rat)

FAS Proteins for Macaca nemestrina (Pig-tailed macaque)

FAS Proteins for Macaca mulatta (Rhesus macaque)

FAS Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

FAS Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

FAS Proteins for Bos taurus (Bovine)

FAS Proteins for Mus musculus (Mouse)

FAS Proteins for Sus scrofa (Pig)


FAS ELISA Kit for Homo sapiens (Human)

FAS ELISA Kit for Rattus norvegicus (Rat)

FAS ELISA Kit for Mus musculus (Mouse)


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