FCGR2B

FCGR2B, or Fcγ Receptor IIb, is an inhibitory Fcγ receptor expressed on the surface of a variety of immune cells. It regulates the immune response through the immunoreceptor tyrosine inhibitory motif (ITIM) contained in its cytoplasmic region, and is able to inhibit excessive immune activation when bound to the Fc fragment of IgG antibodies.FCGR2B plays an important role in regulating the immune response of B cells, dendritic cells, monocytes, and macrophages, among others, and helps to maintain immune self-stabilisation and prevent autoimmune diseases.Abnormalities in the function of FCGR2B have been associated with autoimmune diseases such as systemic lupus erythematosus (SLE). FCGR2B has been implicated in the development of autoimmune diseases such as systemic lupus erythematosus (SLE), and is an important target for immunomodulation and disease treatment.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FCGR2B Antibody (CSB-PA834684)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA834684(FCGR2B Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA834684(FCGR2B Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: CSB-PA834684(FCGR2B Antibody) at dilution 1/850, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds

Human Low affinity immunoglobulin gamma Fc region receptor II-b(FCGR2B) ELISA kit (CSB-EL008541HU)

Validated Data

Code: CSB-EL008541HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.156 ng/mL

Detection Range: 0.625 ng/mL-40 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following FCGR2B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

FCGR2B Antibodies

FCGR2B Proteins

FCGR2B ELISA Kits

FCGR2B Antibodies

FCGR2B Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA785845	Phospho-FCGR2B (Tyr292) Antibody	Human	ELISA,WB
CSB-PA004855	FCGR2B Antibody	Human	WB, ELISA
CSB-PA005208	FCGR2B Antibody	Human	WB, ELISA
CSB-PA008217	Phospho-FCGR2B (Y292) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA834684	FCGR2B Antibody	Human	ELISA,WB,IHC
CSB-PA10839A0Rb	FCGR2B Antibody	Human, Mouse	ELISA, WB, IHC, IF
CSB-PA10839B0Rb	FCGR2B Antibody, HRP conjugated	Human	ELISA
CSB-PA10839C0Rb	FCGR2B Antibody, FITC conjugated	Human
CSB-PA10839D0Rb	FCGR2B Antibody, Biotin conjugated	Human	ELISA

FCGR2B Proteins

FCGR2B Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF008541HU	Recombinant Human Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B)	in vitro E.coli expression system
CSB-YP008541HU1 CSB-EP008541HU1 CSB-BP008541HU1 CSB-EP008541HU1-B	Recombinant Human Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-MP008541HU1	Recombinant Human Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B), partial	Mammalian cell

FCGR2B ELISA Kit

FCGR2B ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL008541HU	Human Low affinity immunoglobulin gamma Fc region receptor II-b(FCGR2B) ELISA kit	serum, plasma, tissue homogenates, cell lysates	0.156 ng/mL

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FCGR2B

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