Frizzled-3 is a protein in humans that is encoded by FZD3 gene. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Activation by Wnt5A stimulates PKC activity via a G-protein-dependent mechanism. Involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
The following FZD3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FZD3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA002580 | FZD3 Antibody |
Human,Mouse | WB, IF, ELISA |
CSB-PA060161 | FZD3 Antibody |
Human,Mouse | WB, IF, ELISA |
CSB-PA129862 | FZD3 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA188693 | FZD3 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA882067ESR1HU | FZD3 Antibody |
Human | ELISA, WB, IHC |
CSB-PA882067ESR2HU | FZD3 Antibody |
Human | ELISA, IHC |
FZD3 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP886099CH CSB-EP886099CH CSB-BP886099CH CSB-MP886099CH CSB-EP886099CH-B |
Recombinant Chicken Frizzled-3 (FZD3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF713959MO | Recombinant Mouse Frizzled-3 (Fzd3) |
in vitro E.coli expression system |
CSB-YP713959MO1 CSB-EP713959MO1 CSB-BP713959MO1 CSB-MP713959MO1 CSB-EP713959MO1-B |
Recombinant Mouse Frizzled-3 (Fzd3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF882067HU | Recombinant Human Frizzled-3 (FZD3) |
in vitro E.coli expression system |
CSB-YP882067HU1 CSB-EP882067HU1 CSB-BP882067HU1 CSB-MP882067HU1 CSB-EP882067HU1-B |
Recombinant Human Frizzled-3 (FZD3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD3 Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-CF009106XBE | Recombinant Xenopus laevis Frizzled-3 (fzd3) |
in vitro E.coli expression system |
CSB-YP009106XBE1 CSB-EP009106XBE1 CSB-BP009106XBE1 CSB-MP009106XBE1 CSB-EP009106XBE1-B |
Recombinant Xenopus laevis Frizzled-3 (fzd3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |