FZD5 Research Reagents

Frizzled-5 is a protein in humans that is encoded by FZD5 gene. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Interacts specifically with Wnt5A to induce the beta-catenin pathway.

The following FZD5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

FZD5 Antibodies

FZD5 Antibodies for Homo sapiens (Human)

FZD5 Proteins

FZD5 Proteins for Xenopus laevis (African clawed frog)

FZD5 Proteins for Homo sapiens (Human)

FZD5 Proteins for Rattus norvegicus (Rat)

FZD5 Proteins for Mus musculus (Mouse)

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