HDAC8, a member of the HDAC family and encoded by the HDAC8 gene, modulates chromatin structure by deacetylating histones, thereby influencing gene expression. It is involved in cell proliferation, differentiation, and apoptosis and is particularly important in nervous and cardiac development. HDAC8's dysregulation is associated with genetic diseases and cancers, making it a potential target for drug development and treatment of related conditions.
Recombinant Human Histone deacetylase 8 (HDAC8) (CSB-EP010244HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HDAC8 Antibody (CSB-PA010244LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA010244LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA010244LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA010244LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following HDAC8 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HDAC8 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010244GA01HU | HDAC8 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA010244LA01HU | HDAC8 Antibody | Human | ELISA, IHC, IF |
CSB-PA010244ESR2HU | HDAC8 Antibody | Human | ELISA, WB, IHC |
CSB-PA010244ESR1HU | HDAC8 Antibody | Human | ELISA, IHC |
CSB-PA795062 | Phospho-HDAC8 (Ser39) Antibody | Human,Mouse,Rat | ELISA,IHC,IF |
CSB-PA000539 | Phospho-HDAC8 (S39) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA002898 | HDAC8 Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA059735 | HDAC8 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA694837 | HDAC8 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA010244EA01HU | HDAC8 Antibody | Human, Rat | ELISA, WB |
HDAC8 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010244HU CSB-BP010244HU CSB-MP010244HU CSB-EP010244HU-B |
Recombinant Human Histone deacetylase 8 (HDAC8) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP010244HU | Recombinant Human Histone deacetylase 8 (HDAC8) | E.coli |