HECTD1 is a protein in humans that is encoded by HECTD1 gene. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.
The following HECTD1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HECTD1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010273GA01HU | HECTD1 Antibody |
Human | ELISA,WB,IHC,IF |
HECTD1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP718193MO CSB-EP718193MO CSB-BP718193MO CSB-MP718193MO CSB-EP718193MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase HECTD1 (Hectd1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HECTD1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP891967HU CSB-EP891967HU CSB-BP891967HU CSB-MP891967HU CSB-EP891967HU-B |
Recombinant Human E3 ubiquitin-protein ligase HECTD1 (HECTD1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |