Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms.
The following IKZF1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IKZF1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA011575GA01HU | IKZF1 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA621668LA01HU | IKZF1 Antibody |
Human | ELISA |
CSB-PA621668LB01HU | IKZF1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA621668LC01HU | IKZF1 Antibody, FITC conjugated |
Human | |
CSB-PA621668LD01HU | IKZF1 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA621668HA01HU | IKZF1 Antibody |
Human | ELISA, WB, IHC, IF |
CSB-PA621668HB01HU | IKZF1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA621668HC01HU | IKZF1 Antibody, FITC conjugated |
Human | |
CSB-PA621668HD01HU | IKZF1 Antibody, Biotin conjugated |
Human | ELISA |
IKZF1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP011575MO CSB-EP011575MO CSB-BP011575MO CSB-MP011575MO CSB-EP011575MO-B |
Recombinant Mouse DNA-binding protein Ikaros (Ikzf1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IKZF1 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP011575CH CSB-EP011575CH CSB-BP011575CH CSB-MP011575CH CSB-EP011575CH-B |
Recombinant Chicken DNA-binding protein Ikaros (IKZF1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IKZF1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Code | Product Name | Source |
---|---|---|
CSB-YP011575OEI CSB-EP011575OEI CSB-BP011575OEI CSB-MP011575OEI CSB-EP011575OEI-B |
Recombinant Oncorhynchus mykiss DNA-binding protein Ikaros (ikzf1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IKZF1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP621668HU CSB-BP621668HU CSB-MP621668HU CSB-EP621668HU-B |
Recombinant Human DNA-binding protein Ikaros (IKZF1) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP621668HU | Recombinant Human DNA-binding protein Ikaros (IKZF1) |
E.coli |