Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 is a protein in humans that is encoded by INPP5D gene. Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Acts as a negative regulator of B-cell antigen receptor signaling. Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems.

INPP5D Antibodies

INPP5D Antibodies for Homo sapiens (Human)

INPP5D Proteins

INPP5D Proteins for Rattus norvegicus (Rat)

INPP5D Proteins for Xenopus laevis (African clawed frog)

INPP5D Proteins for Homo sapiens (Human)

INPP5D Proteins for Mus musculus (Mouse)


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