INPP5D

Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 is a protein in humans that is encoded by INPP5D gene. Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Acts as a negative regulator of B-cell antigen receptor signaling. Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems.

The following INPP5D reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

INPP5D Antibodies

INPP5D Proteins

INPP5D Antibodies

INPP5D Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA284759	INPP5D Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA903060	Phospho-INPP5D (Y1021) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA937511	INPP5D Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA314107	INPP5D Antibody	Human,Mouse,Rat	WB, ELISA
CSB-RA157463A0HU	INPP5D Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IP

INPP5D Proteins

INPP5D Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP311046RA CSB-EP311046RA CSB-BP311046RA CSB-MP311046RA CSB-EP311046RA-B	Recombinant Rat Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (Inpp5d), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

INPP5D Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP740719XBE CSB-EP740719XBE CSB-BP740719XBE CSB-MP740719XBE CSB-EP740719XBE-B	Recombinant Xenopus laevis Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (inpp5d), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

INPP5D Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP842163HU CSB-EP842163HU CSB-BP842163HU CSB-MP842163HU CSB-EP842163HU-B	Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (INPP5D), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

INPP5D Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP861701MO CSB-EP861701MO CSB-BP861701MO CSB-MP861701MO CSB-EP861701MO-B	Recombinant Mouse Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (Inpp5d), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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