IRF6, also known as interferon regulatory factor 6, plays a crucial role in various biological processes. It is a transcription factor belonging to the interferon regulatory factor family. Common aliases include IRF-6. IRF6 functions in regulating gene expression by binding to specific DNA sequences. It is involved in the Wnt signaling pathway, which is essential for cell proliferation, differentiation, and tissue development.
Mutations in the IRF6 gene are associated with several genetic disorders, such as Van der Woude syndrome and popliteal pterygium syndrome. Due to its involvement in these diseases, IRF6 has become a target for drug development. Currently, research is ongoing to explore potential therapeutic agents that can modulate its activity.
IRF6 Antibody (CSB-PA011821LA01HU)
Validated Data
Western Blot
Positive WB detected in: PC-3 whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate, , Mouse liver tissue
All lanes: IRF6 antibody at 4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 54, 42 kDa
Observed band size: 54 kDa
Immunofluorescent analysis of HepG2 cells using CSB-PA011821LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following IRF6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IRF6 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA287048 | IRF6 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA102246 | IRF6 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA011821LA01HU | IRF6 Antibody | Human, Mouse | ELISA, WB, IF |
CSB-PA011821LB01HU | IRF6 Antibody, HRP conjugated | Human | ELISA |
CSB-PA011821LC01HU | IRF6 Antibody, FITC conjugated | Human | |
CSB-PA011821LD01HU | IRF6 Antibody, Biotin conjugated | Human | ELISA |
IRF6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP011821HU CSB-EP011821HU CSB-BP011821HU CSB-MP011821HU CSB-EP011821HU-B |
Recombinant Human Interferon regulatory factor 6 (IRF6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |