KITLG

Kit ligand is a protein in humans that is encoded by KITLG gene. Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.

KITLG Antibodies

KITLG Antibodies for Human

KITLG Antibodies for Homo sapiens (Human)

KITLG Proteins

KITLG Proteins for Homo sapiens (Human)

KITLG Proteins for Neovison vison (American mink) (Mustela vison)

KITLG Proteins for Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)

KITLG Proteins for Capra hircus (Goat)

KITLG Proteins for Equus caballus (Horse)

KITLG Proteins for Gallus gallus (Chicken)

KITLG Proteins for Bos taurus (Bovine)

KITLG Proteins for Sus scrofa (Pig)

KITLG Proteins for Mus musculus (Mouse)

KITLG Proteins for Ovis aries (Sheep)

KITLG Proteins for Rattus norvegicus (Rat)

KITLG Proteins for Felis catus (Cat) (Felis silvestris catus)

KITLG ELISA Kit

KITLG ELISA Kit for Homo sapiens (Human)

KITLG ELISA Kit for Mus musculus (Mouse)

KITLG ELISA Kit for Rattus norvegicus (Rat)

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