KMT2A, or lysine-specific histone methyltransferase 2A, also known as MLL1, is an enzyme encoded by the KMT2A gene and part of the atypical histone methyltransferase family. It regulates gene expression by methylating histone H3 at lysine 4, particularly during cell differentiation and development. KMT2A is integral to cell proliferation, neurodevelopment, hematopoiesis, and oncogenesis, with its dysfunction implicated in genetic diseases and cancer, marking it as a drug development and disease treatment target.
Validated Data
Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
The following KMT2A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
KMT2A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA612015 | KMT2A Antibody | Human,Mouse,Rat | IHC,ELISA |
KMT2A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP014627MO CSB-EP014627MO CSB-BP014627MO CSB-MP014627MO CSB-EP014627MO-B |
Recombinant Mouse Histone-lysine N-methyltransferase MLL (Mll), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |