MAGEA8, also known as Melanoma-associated antigen 8, is a protein coding gene associated with melanoma and benign peritoneal mesothelioma. It is a member of the MAGE family, which plays a role in cancer and immune response. MAGEA8 functions by interacting with other proteins and signaling pathways, contributing to cell cycle regulation and apoptosis. Its expression is often elevated in various cancers, including melanoma, lung cancer, and breast cancer. Research into MAGEA8 has led to the development of modulators that can either enhance or inhibit its activity, offering potential therapeutic applications in cancer immunotherapy and combination therapies.
Recombinant Human Melanoma-associated antigen 8 (MAGEA8) (CSB-EP013334HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MAGEA8 Antibody (CSB-PA013334LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA013334LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA013334LA01HU at dilution of 1:100
Immunofluorescent analysis of PC-3 cells using CSB-PA013334LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following MAGEA8 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MAGEA8 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013334GA01HU | MAGEA8 Antibody | Human | ELISA,WB |
CSB-PA013334LA01HU | MAGEA8 Antibody | Human | ELISA, IHC, IF |
CSB-PA013334LB01HU | MAGEA8 Antibody, HRP conjugated | Human | ELISA |
CSB-PA968714 | MAGEA8 Antibody | Human | ELISA,WB |
MAGEA8 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP013334HU CSB-BP013334HU CSB-MP013334HU CSB-EP013334HU-B |
Recombinant Human Melanoma-associated antigen 8 (MAGEA8) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP013334HU | Recombinant Human Melanoma-associated antigen 8 (MAGEA8) | E.coli |