MAPKAP1

Target of rapamycin complex 2 subunit MAPKAP1 is a protein in humans that is encoded by MAPKAP1 gene. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'.

The following MAPKAP1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

MAPKAP1 Antibodies

MAPKAP1 Proteins

MAPKAP1 Antibodies

MAPKAP1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA013472GA01HU	MAPKAP1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA857767ESR2HU	MAPKAP1 Antibody	Human	ELISA, WB

MAPKAP1 Proteins

MAPKAP1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP013472BO CSB-EP013472BO CSB-BP013472BO CSB-MP013472BO CSB-EP013472BO-B	Recombinant Bovine Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MAPKAP1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Code	Product Name	Source
CSB-YP013472XBF CSB-EP013472XBF CSB-BP013472XBF CSB-MP013472XBF CSB-EP013472XBF-B	Recombinant Xenopus tropicalis Target of rapamycin complex 2 subunit MAPKAP1 (mapkap1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MAPKAP1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP724513RA CSB-EP724513RA CSB-BP724513RA CSB-MP724513RA CSB-EP724513RA-B	Recombinant Rat Target of rapamycin complex 2 subunit MAPKAP1 (Mapkap1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MAPKAP1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP725434PYX CSB-EP725434PYX CSB-BP725434PYX CSB-MP725434PYX CSB-EP725434PYX-B	Recombinant Pongo abelii Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MAPKAP1 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP744162SH CSB-EP744162SH CSB-BP744162SH CSB-MP744162SH CSB-EP744162SH-B	Recombinant Sheep Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MAPKAP1 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP768827XBE CSB-EP768827XBE CSB-BP768827XBE CSB-MP768827XBE CSB-EP768827XBE-B	Recombinant Xenopus laevis Target of rapamycin complex 2 subunit MAPKAP1 (mapkap1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MAPKAP1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP806861MO CSB-EP806861MO CSB-BP806861MO CSB-MP806861MO CSB-EP806861MO-B	Recombinant Mouse Target of rapamycin complex 2 subunit MAPKAP1 (Mapkap1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MAPKAP1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP857767HU CSB-BP857767HU CSB-MP857767HU CSB-EP857767HU-B	Recombinant Human Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP857767HU	Recombinant Human Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1)	E.coli
CSB-EP857767HUc7	Recombinant Human Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1)	E.coli

MAPKAP1 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP893380CH CSB-EP893380CH CSB-BP893380CH CSB-MP893380CH CSB-EP893380CH-B	Recombinant Chicken Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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