The protein corresponding to the gene MPC1 is Mitochondrial Pyruvate Carrier 1. It has no widely - known aliases. MPC1 forms a complex with MPC2 to transport pyruvate across the mitochondrial inner membrane. This process is crucial for pyruvate entry into the tricarboxylic acid (TCA) cycle, fueling ATP production.
MPC1 is involved in the pyruvate - TCA cycle pathway. Dysfunction of MPC1 has been linked to metabolic diseases like diabetes and cancer. In drug R & D, targeting MPC1 holds potential for developing new therapies for these metabolic disorders, although significant work remains before clinical applications.
Validated Data
Western blot analysis of extracts from COLO cells and HeLa cells, using BRP44L antibody.
Immunohistochemistry analysis of paraffin-embedded human heart tissue using BRP44L antibody.
Immunofluorescence analysis of A549 cells, using BRP44L antibody.
The following MPC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MPC1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA206581 | MPC1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA001054 | MPC1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA002817XA01HU | MPC1 Antibody | Homo sapiens (Human) | ELISA, WB (ensure identification of antigen) |