MX1

MX1, also known as Myxovirus resistance 1, is an interferon - induced GTPase. It is commonly referred to as MxA. MX1 plays a crucial role in the innate immune response. It inhibits the replication of various viruses by interfering with their early stages of replication, such as uncoating and nuclear import. It is involved in the type - I interferon signaling pathway.
Dysregulation of MX1 is linked to several diseases, including viral infections like influenza and hepatitis. In the realm of drug research, MX1 has emerged as a potential therapeutic target. Scientists are exploring strategies to enhance its antiviral function, aiming to develop novel antiviral drugs to combat virus - related diseases.

Popular Product:

MX1 Antibody (CSB-PA015249LA01HU)

Validated Data

Western Blot
Positive WB detected in: A549 whole cell lysate, NIH/3T3 whole cell lysate, Hela whole cell lysate
All lanes: MX1 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 76, 56 kDa
Observed band size: 76 kDa

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA015249LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA015249LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunoprecipitating MX1 in Hela whole cell lysate
Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA015249LA01HU in Hela whole cell lysate.For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)
Lane 2: CSB-PA015249LA01HU (4μg) + Hela whole cell lysate (500μg)
Lane 3: Hela whole cell lysate (20μg)

Immunohistochemistry of paraffin-embedded human testicular tissue using CSB-PA015249LA01HU at dilution of 1:100

Human Interferon-induced GTP-binding protein Mx1(MX1) ELISA kit (CSB-EL015249HU)

Validated Data

Code: CSB-EL015249HU

Size: 96T,5×96T,10×96T

Sensitivity: 3.9 pg/mL

Detection Range: 15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following MX1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

MX1 Antibodies

MX1 Proteins

MX1 ELISA Kits

MX1 Antibodies

MX1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA015249GA01HU	MX1 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA616832	MX1 Antibody	Human	ELISA,WB
CSB-PA015249LA01HU	MX1 Antibody	Human, Mouse	ELISA, WB, IHC, IF, IP
CSB-PA015249LB01HU	MX1 Antibody, HRP conjugated	Human	ELISA
CSB-PA015249LC01HU	MX1 Antibody, FITC conjugated	Human
CSB-PA015249LD01HU	MX1 Antibody, Biotin conjugated	Human	ELISA

MX1 Proteins

MX1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP015249HU CSB-EP015249HU CSB-BP015249HU CSB-MP015249HU CSB-EP015249HU-B	Recombinant Human Interferon-induced GTP-binding protein Mx1 (MX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MX1 ELISA Kit

MX1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL015249HU	Human Interferon-induced GTP-binding protein Mx1(MX1) ELISA kit	serum, plasma, urine, tissue homogenates, cell lysates	3.9 pg/mL

Promotions

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily? Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application