OPTN

OPTN, full name optineurin, also known as FIP200-binding protein. It is a multifunctional protein regulating autophagy, apoptosis, DNA damage repair and immune signaling. OPTN dysfunction causes autophagy disorders and correlates with neurodegenerative diseases, glaucoma and cancers. OPTN modulators are under preclinical research for neurological, anti-tumor and inflammatory therapy.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of Baculovirus host and target protein, the LC-MS/MS Analysis result of CSB-BP016363HU could indicate that this peptide derived from Baculovirus-expressed Homo sapiens(Human) OPTN.

OPTN Antibody (CSB-PA548038)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA548038(OPTN Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA548038(OPTN Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)

The following OPTN reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

OPTN Antibodies

OPTN Proteins

OPTN Antibodies

OPTN Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA016363GA01HU	OPTN Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA548038	OPTN Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA924414	OPTN Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA016363ZA01HU	OPTN Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)

OPTN Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA016363XA01DIL	optn Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

OPTN Proteins

OPTN Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP016363DIL CSB-EP016363DIL CSB-BP016363DIL CSB-MP016363DIL CSB-EP016363DIL-B	Recombinant Danio rerio Optineurin (optn), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP016363PYX CSB-EP016363PYX CSB-BP016363PYX CSB-MP016363PYX CSB-EP016363PYX-B	Recombinant Pongo abelii Optineurin (OPTN), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP016363PI CSB-EP016363PI CSB-BP016363PI CSB-MP016363PI CSB-EP016363PI-B	Recombinant Pig Optineurin (OPTN), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP016363MOW CSB-EP016363MOW CSB-BP016363MOW CSB-MP016363MOW CSB-EP016363MOW-B	Recombinant Macaca mulatta Optineurin (OPTN), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP016363MO CSB-EP016363MO CSB-BP016363MO CSB-MP016363MO CSB-EP016363MO-B	Recombinant Mouse Optineurin (Optn)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP016363CH CSB-EP016363CH CSB-BP016363CH CSB-MP016363CH CSB-EP016363CH-B	Recombinant Chicken Optineurin (OPTN), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP016363MOV CSB-EP016363MOV CSB-BP016363MOV CSB-MP016363MOV CSB-EP016363MOV-B	Recombinant Macaca fascicularis Optineurin (OPTN), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP016363HU	Recombinant Human Optineurin (OPTN)	Yeast
CSB-EP016363HU	Recombinant Human Optineurin (OPTN)	E.coli
CSB-BP016363HU	Recombinant Human Optineurin (OPTN)	Baculovirus
CSB-MP016363HU CSB-EP016363HU-B	Recombinant Human Optineurin (OPTN)	Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP016363RA CSB-EP016363RA CSB-BP016363RA CSB-MP016363RA CSB-EP016363RA-B	Recombinant Rat Optineurin (Optn)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

OPTN Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP016363XBE CSB-EP016363XBE CSB-BP016363XBE CSB-MP016363XBE CSB-EP016363XBE-B	Recombinant Xenopus laevis Optineurin (optn), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Promotions

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily? Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application

OPTN

Popular Product: