PIEZO1

PIEZO1, also known as Piezo Type Mechanosensitive Ion Channel Component 1, is a key mechanosensitive ion channel protein. It has no widely - recognized aliases. PIEZO1 senses mechanical forces and converts them into electrical signals by allowing cations to flow through the cell membrane. It is involved in the Hippo signaling pathway.
PIEZO1 is associated with several diseases, such as dehydrated hereditary stomatocytosis. Regarding drug development, research is ongoing. Scientists are exploring substances that can modulate PIEZO1 activity, aiming to develop therapies for related diseases. This could offer new treatment strategies in the future.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PIEZO1 Antibody (CSB-PA852881ESR1HU)

Validated Data

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA852881ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human glioma using CSB-PA852881ESR1HU at dilution of 1:100

The following PIEZO1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PIEZO1 Antibodies

PIEZO1 Proteins

PIEZO1 Antibodies

PIEZO1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA852881ESR1HU	PIEZO1 Antibody	Human	ELISA, IHC

PIEZO1 Proteins

PIEZO1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP852881HU CSB-BP852881HU CSB-MP852881HU CSB-EP852881HU-B	Recombinant Human Piezo-type mechanosensitive ion channel component 1 (PIEZO1), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP852881HU	Recombinant Human Piezo-type mechanosensitive ion channel component 1 (PIEZO1), partial	E.coli

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Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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PIEZO1

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