PRTG

The protein encoded by the PRTG gene, also known as PRTG protein, is a transmembrane protein with a significant role in neural crest differentiation. It functions through complex signaling pathways that are crucial for the development and maintenance of neural crest cells. PRTG is involved in various signaling pathways, including those related to cell growth, migration, and differentiation. Disorders associated with PRTG mutations include neural crest-related diseases. In terms of drug development, Portage Biotech Inc. is advancing the Phase Ia/Ib PORT-6 trial for PRTG, focusing on clinical applications and therapeutic strategies.