RBM42

RBM42, also known as RNA Binding Motif Protein 42, is a protein coding gene with various aliases such as RNA-binding motif protein 42 and RNA Binding Motif Protein 42. RBM42 plays a crucial role in mRNA splicing and translation, acting upstream of or within the negative regulation of mRNA splicing via the spliceosome. It is a component of the U4/U6.U5 tri-snRNP complex and the pre-B complex, which are involved in gene splicing. RBM42 has been associated with diseases like Kleefstra Syndrome 2 and Tarp Syndrome, and its dysregulation may contribute to neurological, facial, cardiac, and musculoskeletal abnormalities. Research on RBM42 is ongoing, with potential implications for drug development targeting RNA splicing and translation processes.