RELA Research Reagents

Transcription factor p65 is a protein in humans that is encoded by RELA gene. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.

The following RELA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

RELA Antibodies

RELA Antibodies for Homo sapiens (Human)

RELA Antibodies for Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

RELA Antibodies for Escherichia coli (strain K12)

RELA Antibodies for Escherichia coli O157:H7

RELA Antibodies for Shigella flexneri

RELA Proteins

RELA Proteins for Gallus gallus (Chicken)

RELA Proteins for Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

RELA Proteins for Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

RELA Proteins for Photobacterium angustum (strain S14 / CCUG 15956) (Vibrio sp. (strain S14 / CCUG 15956))

RELA Proteins for Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)

RELA Proteins for Staphylococcus aureus

RELA Proteins for Escherichia coli (strain K12)

RELA Proteins for Escherichia coli O157:H7

RELA Proteins for Staphylococcus aureus (strain MW2)

RELA Proteins for Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

RELA Proteins for Shigella flexneri

RELA Proteins for Streptomyces antibioticus

RELA Proteins for Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)

RELA Proteins for Myxococcus xanthus

RELA Proteins for Bacillus subtilis (strain 168)

RELA Proteins for Mycobacterium leprae (strain TN)

RELA Proteins for Staphylococcus epidermidis (strain ATCC 35984 / RP62A)

RELA Proteins for Streptococcus dysgalactiae subsp. equisimilis (Streptococcus equisimilis)

RELA Proteins for Staphylococcus aureus (strain MRSA252)

RELA Proteins for Staphylococcus aureus (strain MSSA476)

RELA Proteins for Staphylococcus epidermidis (strain ATCC 12228)

RELA Proteins for Staphylococcus aureus (strain Mu50 / ATCC 700699)

RELA Proteins for Staphylococcus aureus (strain N315)

RELA ELISA Kit

RELA ELISA Kit for Homo sapiens (Human)

RELA ELISA Kit for Mus musculus (Mouse)

RELA Background

Transcription factor p65 is a protein in humans that is encoded by RELA gene. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.

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