Tyrosine-protein kinase RYK is a protein in humans that is encoded by RYK gene. Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation.

RYK Antibodies

RYK Antibodies for Human

RYK Antibodies for Homo sapiens (Human)

RYK Proteins

RYK Proteins for Homo sapiens (Human)

RYK cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL020617HU1 RYK pUC NM_001005861.2
CSB-CL020617HU2 RYK pUC NM_002958.3


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