SCTR, full name secretin receptor, also known as SR, is a G protein-coupled receptor mainly expressed in the pancreas, liver and gastrointestinal tract. It specifically binds secretin peptide, regulates digestive juice secretion and maintains normal gastrointestinal physiological functions.
Abnormal SCTR expression is related to digestive system tumors, pancreatic diseases and gastrointestinal dysfunction. It is also a potential biomarker for pancreatic cancer diagnosis. At present, SCTR-targeted agonists and antagonists are under preclinical research, providing new strategies for digestive tract diseases and malignant tumors.
Recombinant Human Secretin receptor (SCTR) (CSB-CF020865HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SCTR Antibody (CSB-PA020865LA01HU)
Validated Data
Western Blot
Positive WB detected in: Rat liver tissue
All lanes: SCTR antibody at 2.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 51 kDa
Observed band size: 51 kDa
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA020865LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA020865LA01HU at dilution of 1:100
Immunofluorescent analysis of PC-3 cells using CSB-PA020865LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following SCTR reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SCTR Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA020865GA01HU | SCTR Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA257758 | SCTR Antibody | Human | ELISA,WB,IHC |
| CSB-PA336738 | SCTR Antibody | Human | ELISA,IHC |
| CSB-PA020865LA01HU | SCTR Antibody | Human, Rat | ELISA, WB, IHC, IF |
| CSB-PA020865LB01HU | SCTR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA020865LC01HU | SCTR Antibody, FITC conjugated | Human | |
| CSB-PA020865LD01HU | SCTR Antibody, Biotin conjugated | Human | ELISA |
SCTR Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF020865HU | Recombinant Human Secretin receptor (SCTR) | in vitro E.coli expression system |
| CSB-YP020865HU1 CSB-EP020865HU1 CSB-BP020865HU1 CSB-MP020865HU1 CSB-EP020865HU1-B |
Recombinant Human Secretin receptor (SCTR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SCTR Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF020865MO | Recombinant Mouse Secretin receptor (Sctr) | in vitro E.coli expression system |
| CSB-YP020865MO1 CSB-EP020865MO1 CSB-BP020865MO1 CSB-MP020865MO1 CSB-EP020865MO1-B |
Recombinant Mouse Secretin receptor (Sctr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SCTR Proteins for Oryctolagus cuniculus (Rabbit)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF020865RB | Recombinant Rabbit Secretin receptor (SCTR) | in vitro E.coli expression system |
| CSB-YP020865RB1 CSB-EP020865RB1 CSB-BP020865RB1 CSB-MP020865RB1 CSB-EP020865RB1-B |
Recombinant Rabbit Secretin receptor (SCTR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SCTR Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF020865RA | Recombinant Rat Secretin receptor (Sctr) | in vitro E.coli expression system |
| CSB-YP020865RA1 CSB-EP020865RA1 CSB-BP020865RA1 CSB-MP020865RA1 CSB-EP020865RA1-B |
Recombinant Rat Secretin receptor (Sctr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |