The SEMA4A gene encodes the Semaphorin-4A protein, also known as Sema4A. This protein plays a crucial role in priming antigen-specific T-cells and promoting differentiation of Th1 T-helper cells, thereby contributing to adaptive immunity. SEMA4A interacts with Plexin D1 receptor, activating the Akt pathway in lung fibroblasts. Its dysregulation is implicated in Th17 cell-mediated neuroinflammation and various diseases, including cancer and fibrosis. Research on SEMA4A signaling pathways has opened avenues for potential therapeutic targets in drug development.
SEMA4A Antibody (CSB-PA004061)
Validated Data
Western Blot analysis of Jurkat cells using SEMA4A Polyclonal Antibody
Human Semaphorin-4A(SEMA4A) ELISA kit (CSB-EL020987HU)
Validated Data
Code: CSB-EL020987HU
Size: 96T,5×96T,10×96T
Sensitivity: 0.078 ng/mL
Detection Range: 0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following SEMA4A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SEMA4A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020987GA01HU | SEMA4A Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA004061 | SEMA4A Antibody | Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
CSB-PA164146 | SEMA4A Antibody | Human | ELISA,IHC |
CSB-PA954171 | SEMA4A Antibody | Human | ELISA,IHC |
SEMA4A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP884461HU CSB-EP884461HU CSB-BP884461HU CSB-MP884461HU CSB-EP884461HU-B |
Recombinant Human Semaphorin-4A (SEMA4A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SEMA4A ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL020987HU | Human Semaphorin-4A(SEMA4A) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/mL |