SLC13A5 encodes the sodium-coupled citrate transporter 2 (NaCT2), also known as NaDC3. This protein plays a crucial role in cellular metabolism by transporting citrate across the cell membrane. It functions as an electrogenic sodium/citrate symporter. The SLC13A5 is involved in the tricarboxylic acid (TCA) cycle and fatty acid synthesis pathways.
Mutations in the SLC13A5 gene have been linked to early infantile epileptic encephalopathy - 39 (EIEE39), a severe neurological disorder. Currently, research on drugs targeting SLC13A5 is in progress, aiming to develop therapies for EIEE39 and related metabolic diseases.
SLC13A5 Antibody (CSB-PA768239LA01HU)
Validated Data
Western Blot
Positive WB detected in: HepG2 whole cell lysate, Rat liver tissue, Mouse heart tissue
All lanes: SLC13A5 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 64, 59, 62 kDa
Observed band size: 64, 59 kDa
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA768239LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA768239LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following SLC13A5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SLC13A5 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA768239LA01HU | SLC13A5 Antibody | Human, Mouse, Rat | ELISA, WB, IHC, IF |
CSB-PA768239LB01HU | SLC13A5 Antibody, HRP conjugated | Human | ELISA |
CSB-PA768239LC01HU | SLC13A5 Antibody, FITC conjugated | Human | |
CSB-PA768239LD01HU | SLC13A5 Antibody, Biotin conjugated | Human | ELISA |
SLC13A5 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP768239HU CSB-EP768239HU CSB-BP768239HU CSB-MP768239HU CSB-EP768239HU-B |
Recombinant Human Solute carrier family 13 member 5 (SLC13A5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |