SLC17A5, a member of the solute carrier family 17, is a transmembrane protein characterized by multiple transmembrane domains. These domains enable SLC17A5 to form channels or transporters on the cell membrane, regulating the transport of specific substances between the intracellular and extracellular environments. The protein encoded by the SLC17A5 gene is known as Sialin, which plays a pivotal role in the transport and regulation of solutes in the nervous system and muscles. At the cell membrane, Sialin is responsible for the transport of sialic acid, a substance that performs crucial functions in the nervous system. By regulating the transport of sialic acid, Sialin influences the normal function and signal transduction of nerve cells. The signaling pathways involving SLC17A5 are primarily linked to the functions of the nervous system and muscles. When mutations occur in SLC17A5, the function of Sialin protein is compromised, leading to abnormalities in the transport and regulation of sialic acid within cells. This dysregulation disrupts the normal signal transduction of nerve cells, triggering a range of neurological and muscular disease manifestations.
Recombinant Human Sialin (SLC17A5), partial
Source: Yeast
Source: E.coli
Source: Baculovirus
Source: Mammalian cell
Source: In Vivo Biotinylation in E.coli
The following SLC17A5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SLC17A5 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA021421GA01HU | SLC17A5 Antibody |
Human,Mouse,Rat | ELISA,WB |
SLC17A5 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP803910MO CSB-EP803910MO CSB-BP803910MO CSB-MP803910MO CSB-EP803910MO-B |
Recombinant Mouse Sialin (Slc17a5), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC17A5 Proteins for Ovis aries (Sheep)
Code | Product Name | Source |
---|---|---|
CSB-YP878777SH CSB-EP878777SH CSB-BP878777SH CSB-MP878777SH CSB-EP878777SH-B |
Recombinant Sheep Sialin (SLC17A5), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC17A5 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP889090HU CSB-EP889090HU CSB-BP889090HU CSB-MP889090HU CSB-EP889090HU-B |
Recombinant Human Sialin (SLC17A5), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |