SNRNP200

SNRNP200, also known as U5 small nuclear ribonucleoprotein 200 kDa helicase, is a critical protein encoded by the SNRNP200 gene. It plays a key role in pre - mRNA splicing, where it uses its helicase activity to unwind RNA duplexes, facilitating the proper assembly and rearrangement of the spliceosome. This protein is involved in the spliceosome - mediated splicing pathway.
Mutations in SNRNP200 are associated with retinitis pigmentosa, a group of genetic eye disorders that lead to progressive vision loss. Currently, research is underway to develop targeted therapies. These efforts aim to understand the exact mechanisms of SNRNP200 - related pathogenesis to design effective drugs for treating associated diseases.