TRPC5

TRPC5, or classical transient receptor potential 5, is a non-selective cation channel primarily expressed in brain tissue with additional presence in the liver and kidneys. It facilitates membrane depolarization and intracellular calcium influx, modulating physiological processes like emotional response, neural signal transmission, and renal function. TRPC5's dysfunction is implicated in conditions such as anxiety, depression, and kidney diseases, making it a promising target for drug development.