Tuberin is a protein in humans that is encoded by TSC2 gene. In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.

TSC2 Antibodies

TSC2 Antibodies for Homo sapiens (Human)

TSC2 Antibodies for Human

TSC2 Antibodies for Mus musculus (Mouse)

TSC2 Proteins

TSC2 Proteins for Rattus norvegicus (Rat)

TSC2 Proteins for Homo sapiens (Human)

TSC2 Proteins for Mus musculus (Mouse)


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