Tuberin is a protein in humans that is encoded by TSC2 gene. In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.

TSC2 Antibodies

TSC2 Antibodies for Homo sapiens (Human)

Code Product Name Species Reactivity Application
CSB-PA004343 TSC2 Antibody Human,Mouse,Rat WB,IHC,IF,ELISA
CSB-PA060012 Phospho-TSC2 (S939) Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA060013 Phospho-TSC2 (T1462) Antibody Human,Mouse,Rat WB,IHC,IF,ELISA
CSB-PA060014 Phospho-TSC2 (Y1571) Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA060015 TSC2 Antibody Human,Mouse,Rat IHC,ELISA
CSB-PA060016 TSC2 Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA776368 TSC2 Antibody Human,Mouse,Rat ELISA,IHC
CSB-PA955576 TSC2 Antibody Human,Mouse,Rat ELISA,IHC
CSB-PA980506 TSC2 Antibody Human,Mouse,Rat ELISA,WB,IHC

TSC2 Antibodies for Human

Code Product Name Species Reactivity Application
CSB-PA343033LA01HU TSC2 Antibody Human ELISA, IF
CSB-PA343033LB01HU TSC2 Antibody, HRP conjugated Human ELISA
CSB-PA343033LC01HU TSC2 Antibody, FITC conjugated Human ELISA
CSB-PA343033LD01HU TSC2 Antibody, Biotin conjugated Human ELISA

TSC2 Antibodies for Mus musculus (Mouse)

Code Product Name Species Reactivity Application
CSB-PA730717XA01MO TSC2 Antibody Mus musculus (Mouse) ELISA, WB (ensure identification of antigen)

TSC2 Proteins

TSC2 Proteins for Rattus norvegicus (Rat)

Code Product Name Source
CSB-YP342640RA Recombinant Rat Tuberin(Tsc2) ,partial,Yeast Yeast
CSB-EP342640RA Recombinant Rat Tuberin(Tsc2) ,partial,Escherichia Coli E.coli
CSB-BP342640RA Recombinant Rat Tuberin(Tsc2) ,partial,Baculovirus Baculovirus
CSB-MP342640RA Recombinant Rat Tuberin(Tsc2) ,partial,Mammalian cell Mammalian cell

TSC2 Proteins for Homo sapiens (Human)

Code Product Name Source
CSB-YP343033HU Recombinant Human Tuberin(TSC2) ,partial,Yeast Yeast
CSB-EP343033HU Recombinant Human Tuberin(TSC2) ,partial,Escherichia Coli E.coli
CSB-BP343033HU Recombinant Human Tuberin(TSC2) ,partial,Baculovirus Baculovirus
CSB-MP343033HU Recombinant Human Tuberin(TSC2) ,partial,Mammalian cell Mammalian cell

TSC2 Proteins for Mus musculus (Mouse)

Code Product Name Source
CSB-YP730717MO Recombinant Mouse Tuberin(Tsc2) ,partial,Yeast Yeast
CSB-EP730717MO Recombinant Mouse Tuberin(Tsc2) ,partial,Escherichia Coli E.coli
CSB-BP730717MO Recombinant Mouse Tuberin(Tsc2) ,partial,Baculovirus Baculovirus
CSB-MP730717MO Recombinant Mouse Tuberin(Tsc2) ,partial,Mammalian cell Mammalian cell


TSC2 cDNA for Rattus norvegicus (Rat)

Code Product Name Vector Accession NO.
CSB-CL342640RA Tsc2 pUC NM_012680.2


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