USP17L1

USP17L1 encodes the ubiquitin-specific protease 17-like protein 1, a deubiquitinating enzyme that removes ubiquitin moieties from target proteins, thereby regulating protein stability and degradation. It shares structural homology with the USP17 family and is involved in cell cycle progression and proliferation pathways. Aberrant USP17L1 expression has been linked to colorectal cancer, where it may promote tumor growth by stabilizing oncoproteins. Current research focuses on its role in Wnt/β-catenin signaling, though specific inhibitors remain in preclinical development stages.