USP33

USP3 is a pivotal deubiquitinase that curbs cellular proteasome degradation by removing ubiquitin from substrate proteins, thereby influencing cellular signaling, autophagy, centrosome amplification, and tumorigenesis. This enzyme interacts with specific proteins like CP110, modulating their stability and activity, which is crucial for centrosome biosynthesis and broader cellular functions. The expression levels of USP33 have been associated with a variety of diseases, with significant effects on cancer prevention, treatment outcomes, and disease prognosis. These findings suggest that USP33 could serve as a promising new target for therapeutic intervention.

Popular Product:

USP33 Antibody (CSB-PA840583LA01HU)

Validated Data

Western Blot
Positive WB detected in: Hela whole cell lysate
All lanes: USP33 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 107, 104, 94 kDa
Observed band size: 107 kDa

Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA840583LA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA840583LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The following USP33 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

USP33 Antibodies

USP33 Proteins

USP33 Antibodies

USP33 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA025724GA01HU	USP33 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA840583LA01HU	USP33 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA840583LB01HU	USP33 Antibody, HRP conjugated	Human	ELISA
CSB-PA840583LC01HU	USP33 Antibody, FITC conjugated	Human

USP33 Proteins

USP33 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP840583HU CSB-EP840583HU CSB-BP840583HU CSB-MP840583HU CSB-EP840583HU-B	Recombinant Human Ubiquitin carboxyl-terminal hydrolase 33 (USP33), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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