VTN

VTN, recognized as vitronectin, is a multifaceted glycoprotein synthesized primarily by the liver. Found abundantly in plasma and extracellular matrices, VTN interfaces with cell surface receptors and matrix components through its functional domains to modulate cell adhesion, migration, proliferation, and matrix remodeling. It is vital for tissue homeostasis, angiogenesis, and inflammation. Dysregulation of VTN is associated with a spectrum of diseases, including metabolic disorders, cancer, and cardiovascular conditions, highlighting its intricate role in pathophysiology. VTN is a pivotal molecule for studying cell-matrix interactions and a promising target for diagnostic and therapeutic applications.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

VTN Antibody (CSB-PA029544EA01HU)

Validated Data

Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: VTN antibody at 4.6µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa

IHC image of CSB-PA029544EA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human vitronectin (VTN) ELISA Kit (CSB-E08983h)

Validated Data

Code: CSB-E08983h

Size: 96T,5×96T,10×96T

Sensitivity: 0.39 ng/mL

Detection Range: 1.56 ng/mL-100 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following VTN reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

VTN Antibodies

VTN Proteins

VTN ELISA Kits

VTN Antibodies

VTN Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA025944GA01HU	VTN Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA025944ESR1HU	VTN Antibody	Human	ELISA, WB, IHC, IP
CSB-PA025944ESR2HU	VTN Antibody	Human	ELISA, IHC
CSB-PA060080	VTN Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA101139	VTN Antibody	Human	ELISA,IHC
CSB-PA213506	VTN Antibody	Human	ELISA,IHC
CSB-PA025944EA01HU	VTN Antibody	Human, Mouse	ELISA, WB, IHC, IF
CSB-PA025944EC01HU	VTN Antibody, FITC conjugated	Human
CSB-PA025944ED01HU	VTN Antibody, Biotin conjugated	Human	ELISA
CSB-PA029544EA01HU	VTN Antibody	Human	ELISA, WB, IHC
CSB-PA029544EB01HU	VTN Antibody, HRP conjugated	Human	ELISA
CSB-PA029544EC01HU	VTN Antibody, FITC conjugated	Human
CSB-PA029544ED01HU	VTN Antibody, Biotin conjugated	Human	ELISA

VTN Proteins

VTN Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP025944RB CSB-EP025944RB CSB-BP025944RB CSB-MP025944RB CSB-EP025944RB-B	Recombinant Rabbit Vitronectin (VTN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

VTN Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP025944MO CSB-BP025944MO CSB-MP025944MO CSB-EP025944MO-B	Recombinant Mouse Vitronectin (Vtn)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

VTN Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP025944PI CSB-EP025944PI CSB-BP025944PI CSB-MP025944PI CSB-EP025944PI-B	Recombinant Pig Vitronectin (VTN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

VTN Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP025944HU CSB-BP025944HU CSB-MP025944HU CSB-EP025944HU-B	Recombinant Human Vitronectin (VTN)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP025944HU	Recombinant Human Vitronectin (VTN)	E.coli
CSB-MP025944HU-WD1	Recombinant Human Vitronectin (VTN) (Active)	Mammalian cell
CSB-MP025944HU-WD2	Recombinant Human Vitronectin (VTN) (Active)	Mammalian cell

VTN ELISA Kit

VTN ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E08983h	Human vitronectin (VTN) ELISA Kit	serum, plasma, tissue homogenates	0.39 ng/mL

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VTN

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