A35R

A35R is a core protein of the Monkeypox virus (MPXV). This viral component plays a significant role, especially in the envelopes of intracellular enveloped virus particles (IEV) and extracellular enveloped virus particles (EEV). It shares homology with notochordal poxvirus A33R and is involved in the intercellular and long-distance spread of the virus, which is vital for its transmission. A35R contributes to the viral replication cycle by regulating the movement of viral particles, actin tail nucleation, and potentially the formation and release of the viral envelope. Biologically, the A35R protein is a key target for vaccine development and antiviral research, offering significant insights into the virus's transmission and infection mechanisms.

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Recombinant Vaccinia virus Protein A35 (A35R)