ABCB6, a crucial member of the ATP-binding cassette transporter subfamily B, exhibits a structural characteristic that enables it to recognize and bind specific substrates for their translocation across cellular membranes. Functionally, ABCB6 primarily facilitates the transport of various essential intracellular substances, including phospholipids and ions, vital for maintaining normal cellular functions and metabolism. Additionally, it plays a role in maintaining metal ion homeostasis and regulating heme levels. Although the specific signaling pathways involving ABCB6 remain incompletely understood, research suggests that its transport function may be modulated by intracellular signaling molecules. Mutations or aberrant expressions of ABCB6 have been implicated in the pathogenesis of certain diseases.
Recombinant Human ATP-binding cassette sub-family B member 6, mitochondrial (ABCB6), partial
Source: Yeast
Source: E.coli
Source: Baculovirus
Source: Mammalian cell
Source: In Vivo Biotinylation in E.coli
The following ABCB6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ABCB6 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA001052GA01HU | ABCB6 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA976738 | ABCB6 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA273896 | ABCB6 Antibody |
Human,Mouse,Rat | ELISA,WB |
ABCB6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP889063HU CSB-EP889063HU CSB-BP889063HU CSB-MP889063HU CSB-EP889063HU-B |
Recombinant Human ATP-binding cassette sub-family B member 6, mitochondrial (ABCB6), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |