ACP1

The gene ACP1 encodes for the protein Acid Phosphatase 1 (ACP1), also known as PPAC. ACP1 is a lysosomal enzyme that plays a role in bone resorption and cell signaling. It is involved in the regulation of calcium and phosphate metabolism, and its activity is crucial for the maintenance of bone and mineral homeostasis. ACP1 is also associated with various signaling pathways, including the Wnt and BMP pathways, which are important for cell differentiation and development. In terms of related diseases, ACP1 mutations have been linked to osteopetrosis and other skeletal disorders. In the realm of drug development, research is ongoing to explore the potential of ACP1 inhibitors for treating bone-related diseases and cancer.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP001176HUe1 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ACP1.

ACP1 Antibody (CSB-PA001176ESR2HU)

Validated Data

Western blot
All lanes: Low molecular weight phosphotyrosine protein phosphatase antibody at 4μg/ml + HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 19, 18, 15, 13 kDa
Observed band size: 19 kDa

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA001176ESR2HU at dilution of 1:100

The following ACP1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ACP1 Antibodies

ACP1 Proteins

ACP1 Antibodies

ACP1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA001176ESR2HU	ACP1 Antibody	Human	ELISA, WB, IHC
CSB-PA001176ESR1HU	ACP1 Antibody	Human	ELISA

ACP1 Proteins

ACP1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP001176HU CSB-BP001176HU CSB-MP001176HU CSB-EP001176HU-B	Recombinant Human Low molecular weight phosphotyrosine protein phosphatase (ACP1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP001176HU	Recombinant Human Low molecular weight phosphotyrosine protein phosphatase (ACP1)	E.coli
CSB-EP001176HUe1	Recombinant Human Low molecular weight phosphotyrosine protein phosphatase (ACP1)	E.coli

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ACP1

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