Scaffold protein that plays an important role in assembling signaling complexes downstream of several types of G protein-coupled receptors. Activates RHOA in response to signaling via G protein-coupled receptors via its function as Rho guanine nucleotide exchange factor. May also activate other Rho family members. Part of a kinase signaling complex that links ADRA1A and ADRA1B adrenergic receptor signaling to the activation of downstream p38 MAP kinases, such as MAPK11 and MAPK14. Part of a signaling complex that links ADRA1B signaling to the activation of RHOA and IKBKB/IKKB, leading to increased NF-kappa-B transcriptional activity. Part of a RHOA-dependent signaling cascade that mediates responses to lysophosphatidic acid (LPA), a signaling molecule that activates G-protein coupled receptors and potentiates transcriptional activation of the glucocorticoid receptor NR3C1. Part of a signaling cascade that stimulates MEF2C-dependent gene expression in response to lysophosphatidic acid (LPA) (By similarity).
The following AKAP13 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
AKAP13 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA613265ESR1HU | AKAP13 Antibody |
Human | ELISA, IHC |
CSB-PA006793 | AKAP13 Antibody |
Human | WB, IHC, ELISA |
AKAP13 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP613265HU CSB-EP613265HU CSB-BP613265HU CSB-MP613265HU CSB-EP613265HU-B |
Recombinant Human A-kinase anchor protein 13 (AKAP13), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |