AP-2 complex subunit alpha-1 is a protein in humans that is encoded by AP2A1 gene. Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation.
The following AP2A1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
AP2A1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA001869GA01HU | AP2A1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA001869ESR1HU | AP2A1 Antibody | Human | ELISA, IHC |
CSB-PA995615 | AP2A1 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA086984 | AP2A1 Antibody | Human,Mouse | ELISA,WB,IHC |
AP2A1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP001869MO CSB-EP001869MO CSB-BP001869MO CSB-MP001869MO CSB-EP001869MO-B |
Recombinant Mouse AP-2 complex subunit alpha-1 (Ap2a1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AP2A1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP001869HU CSB-EP001869HU CSB-BP001869HU CSB-MP001869HU CSB-EP001869HU-B |
Recombinant Human AP-2 complex subunit alpha-1 (AP2A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |