AP2A1

AP-2 complex subunit alpha-1 is a protein in humans that is encoded by AP2A1 gene. Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation.

AP2A1 Antibodies

AP2A1 Antibodies for Homo sapiens (Human)

AP2A1 Antibodies for Human

AP2A1 Proteins

AP2A1 Proteins for Mus musculus (Mouse)

AP2A1 Proteins for Homo sapiens (Human)

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