AP-2 complex subunit alpha-2 is a protein in humans that is encoded by AP2A2 gene. Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation.
The following AP2A2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
AP2A2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA001870DSR2HU | AP2A2 Antibody | Human, Mouse | ELISA, WB, IHC |
AP2A2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
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CSB-YP001870MO CSB-EP001870MO CSB-BP001870MO CSB-MP001870MO CSB-EP001870MO-B |
Recombinant Mouse AP-2 complex subunit alpha-2 (Ap2a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AP2A2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP001870RA CSB-EP001870RA CSB-BP001870RA CSB-MP001870RA CSB-EP001870RA-B |
Recombinant Rat AP-2 complex subunit alpha-2 (Ap2a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AP2A2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP001870HU CSB-EP001870HU CSB-BP001870HU CSB-MP001870HU CSB-EP001870HU-B |
Recombinant Human AP-2 complex subunit alpha-2 (AP2A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AP2A2 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP613132BO CSB-EP613132BO CSB-BP613132BO CSB-MP613132BO CSB-EP613132BO-B |
Recombinant Bovine AP-2 complex subunit alpha-2 (AP2A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |