ARFGAP1 Research Reagents

ADP-ribosylation factor GTPase-activating protein 1 is a protein in humans that is encoded by ARFGAP1 gene. GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).

The following ARFGAP1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ARFGAP1 Antibodies

ARFGAP1 Antibodies for Homo sapiens (Human)

ARFGAP1 Proteins

ARFGAP1 Proteins for Rattus norvegicus (Rat)

ARFGAP1 Proteins for Homo sapiens (Human)

ARFGAP1 Proteins for Mus musculus (Mouse)


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