ARID1A, the AT-rich binding domain 1A gene, which is an important member of the SWI/SNF chromatin remodelling complex family, is mainly derived from the position on chromosome 1p36.11.The mechanism of action of ARID1A includes non-specific binding to DNA and regulation of cellular life activities such as the cell cycle, cell proliferation, DNA damage repair, etc.ARID1A acts as a tumour suppressor, mutated or absent in a variety of tumours, has an important impact on tumour development, and its loss of function may lead to enhanced proliferation and invasiveness of tumour cells.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP002058HU1 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ARID1A.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP002058HU1 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ARID1A.
ARID1A Antibody (CSB-PA040400)
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA040400(ARID1A Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA040400(ARID1A Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)
The following ARID1A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ARID1A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA040400 | ARID1A Antibody | Human,Mouse | ELISA,IHC |
CSB-PA226311 | ARID1A Antibody | Human,Mouse | ELISA,WB |
CSB-PA002058LA01HU | ARID1A Antibody | Human | ELISA, IHC |
CSB-PA002058LB01HU | ARID1A Antibody, HRP conjugated | Human | ELISA |
ARID1A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP002058MO CSB-EP002058MO CSB-BP002058MO CSB-MP002058MO CSB-EP002058MO-B |
Recombinant Mouse AT-rich interactive domain-containing protein 1A (Arid1a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ARID1A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP002058HU CSB-EP002058HU CSB-BP002058HU CSB-MP002058HU CSB-EP002058HU-B |
Recombinant Human AT-rich interactive domain-containing protein 1A (ARID1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP002058HU1 | Recombinant Human AT-rich interactive domain-containing protein 1A (ARID1A), partial | E.coli |
CSB-BP002058HU1 | Recombinant Human AT-rich interactive domain-containing protein 1A (ARID1A), partial | Baculovirus |