ARID5B

Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Acts by forming a complex with phosphorylated PHF2, which mediates demethylation at Lys-336, leading to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes. Overexpression leads to induction of smooth muscle marker genes, suggesting that it may also act as a regulator of smooth muscle cell differentiation and proliferation. Represses the cytomegalovirus enhancer.

The following ARID5B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ARID5B Antibodies

ARID5B Proteins

ARID5B Antibodies

ARID5B Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA002067XA01DIL	arid5b Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

ARID5B Proteins

ARID5B Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP002067BO CSB-EP002067BO CSB-BP002067BO CSB-MP002067BO CSB-EP002067BO-B	Recombinant Bovine AT-rich interactive domain-containing protein 5B (ARID5B), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ARID5B Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP002067DO CSB-EP002067DO CSB-BP002067DO CSB-MP002067DO CSB-EP002067DO-B	Recombinant Dog AT-rich interactive domain-containing protein 5B (ARID5B), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ARID5B Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP002067DIL CSB-EP002067DIL CSB-BP002067DIL CSB-MP002067DIL CSB-EP002067DIL-B	Recombinant Danio rerio AT-rich interactive domain-containing protein 5B (arid5b), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ARID5B Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP623937HU CSB-EP623937HU CSB-BP623937HU CSB-MP623937HU CSB-EP623937HU-B	Recombinant Human AT-rich interactive domain-containing protein 5B (ARID5B), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ARID5B Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP716952CH CSB-EP716952CH CSB-BP716952CH CSB-MP716952CH CSB-EP716952CH-B	Recombinant Chicken AT-rich interactive domain-containing protein 5B (ARID5B), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ARID5B Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP805924MO CSB-EP805924MO CSB-BP805924MO CSB-MP805924MO CSB-EP805924MO-B	Recombinant Mouse AT-rich interactive domain-containing protein 5B (Arid5b), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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