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Cysteine protease ATG4B is a protein in humans that is encoded by ATG4B gene. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
The following ATG4B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ATG4B Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA002290GA01HU | ATG4B Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA138409 | ATG4B Antibody |
Human,Mouse | ELISA,WB,IHC |
| CSB-PA008332 | ATG4B Antibody |
Human,Mouse | WB, IHC, ELISA |
| CSB-PA123924 | ATG4B Antibody |
Human,Mouse | ELISA,WB |
| CSB-PA274804 | ATG4B Antibody |
Human | ELISA,IHC |
| CSB-PA529850 | ATG4B Antibody |
Human,Mouse,Rat | IHC,ELISA |
| CSB-PA002290LA01HU | ATG4B Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA002290LB01HU | ATG4B Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA002290LC01HU | ATG4B Antibody, FITC conjugated |
Human | |
| CSB-PA002290LD01HU | ATG4B Antibody, Biotin conjugated |
Human | ELISA |
ATG4B Antibodies for Arabidopsis thaliana (Mouse-ear cress)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA878671XA01DOA | ATG4B Antibody |
Arabidopsis thaliana | ELISA, WB (ensure identification of antigen) |
ATG4B Antibodies for Oryza sativa subsp. indica (Rice)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA652064XA01OFF | ATG4B Antibody |
Oryza sativa subsp. indica (Rice) | ELISA, WB (ensure identification of antigen) |
ATG4B Antibodies for Oryza sativa subsp. japonica (Rice)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA767123XA01OFG | ATG4B Antibody |
Oryza sativa subsp. japonica (Rice) | ELISA, WB (ensure identification of antigen) |
ATG4B Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA738547XA01DIL | atg4b Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
ATG4B Proteins for Oryza sativa subsp. indica (Rice)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP652064OFF CSB-EP652064OFF CSB-BP652064OFF CSB-MP652064OFF CSB-EP652064OFF-B |
Recombinant Oryza sativa subsp. indica Cysteine protease ATG4B(ATG4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4B Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP720642XBE CSB-EP720642XBE CSB-BP720642XBE CSB-MP720642XBE CSB-EP720642XBE-B |
Recombinant Xenopus laevis Cysteine protease ATG4B(atg4b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4B Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP738547DIL CSB-EP738547DIL CSB-BP738547DIL CSB-MP738547DIL CSB-EP738547DIL-B |
Recombinant Danio rerio Cysteine protease ATG4B(atg4b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4B Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP754291BO CSB-EP754291BO CSB-BP754291BO CSB-MP754291BO CSB-EP754291BO-B |
Recombinant Bovine Cysteine protease ATG4B(ATG4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4B Proteins for Gallus gallus (Chicken)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP757670CH CSB-EP757670CH CSB-BP757670CH CSB-MP757670CH CSB-EP757670CH-B |
Recombinant Chicken Cysteine protease ATG4B(ATG4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4B Proteins for Oryza sativa subsp. japonica (Rice)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP767123OFG CSB-EP767123OFG CSB-BP767123OFG CSB-MP767123OFG CSB-EP767123OFG-B |
Recombinant Oryza sativa subsp. japonica Cysteine protease ATG4B(ATG4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4B Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP807332MO CSB-EP807332MO CSB-BP807332MO CSB-MP807332MO CSB-EP807332MO-B |
Recombinant Mouse Cysteine protease ATG4B(Atg4b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4B Proteins for Arabidopsis thaliana (Mouse-ear cress)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP878671DOA CSB-EP878671DOA CSB-BP878671DOA CSB-MP878671DOA CSB-EP878671DOA-B |
Recombinant Arabidopsis thaliana Cysteine protease ATG4b(ATG4B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Cysteine protease ATG4B is a protein in humans that is encoded by the ATG4B gene. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2, and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. It has also an activity of the delipidating enzyme for the PE-conjugated forms.
