ATRX, also known as alpha thalassemia/mental retardation syndrome X-linked, is a protein-coding gene. The corresponding protein is Alpha-thalassemia mental retardation syndrome X-linked protein, commonly known as ATRX. It functions in chromatin remodeling and gene regulation. ATRX is involved in the Fanconi anemia pathway and homologous recombination.
Mutations in ATRX are associated with alpha-thalassemia/mental retardation syndrome. In drug development, research is focusing on targeting the ATRX-related pathways to treat cancers with ATRX mutations, aiming to restore normal chromatin function and gene expression.
ATRX Antibody (CSB-PA002437LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA002437LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA002437LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA002437LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following ATRX reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ATRX Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA947796 | ATRX Antibody | Human,Mouse | ELISA,IF |
CSB-PA030136 | ATRX Antibody | Human,Mouse | IF, ELISA |
CSB-PA002437LA01HU | ATRX Antibody | Human | ELISA, IHC, IF |
CSB-PA002437LB01HU | ATRX Antibody, HRP conjugated | Human | ELISA |
CSB-PA002437LC01HU | ATRX Antibody, FITC conjugated | Human |
ATRX Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP002437HU CSB-EP002437HU CSB-BP002437HU CSB-MP002437HU CSB-EP002437HU-B |
Recombinant Human Transcriptional regulator ATRX (ATRX), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |