Bone morphogenetic protein receptor type-2 is a protein in humans that is encoded by BMPR2 gene. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
BMPR2 Antibodies for Homo sapiens (Human)
|Code||Product Name||Species Reactivity||Application|
BMPR2 Proteins for Mus musculus (Mouse)
BMPR2 Proteins for Homo sapiens (Human)
BMPR2 ELISA Kit for Homo sapiens (Human)
|Code||Product Name||Sample Types||Sensitivity|
|CSB-E04516h||serum, plasma, tissue homogenates, cell lysates||1.56 pg/mL|