Bone morphogenetic protein receptor type-2 is a protein in humans that is encoded by BMPR2 gene. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
The following BMPR2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
BMPR2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA002752GA01HU | BMPR2 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA477402 | BMPR2 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA962181 | BMPR2 Antibody |
Human,Mouse | ELISA,IHC |
BMPR2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP002752MO CSB-EP002752MO CSB-BP002752MO CSB-MP002752MO CSB-EP002752MO-B |
Recombinant Mouse Bone morphogenetic protein receptor type-2 (Bmpr2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BMPR2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618807HU CSB-EP618807HU CSB-BP618807HU CSB-MP618807HU CSB-EP618807HU-B |
Recombinant Human Bone morphogenetic protein receptor type-2 (BMPR2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BMPR2 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04516h | Human Bone morphogenetic protein receptor Ⅱ,BMPR-Ⅱ ELISA Kit |
serum, plasma, tissue homogenates, cell lysates | 1.56 pg/mL |