CASZ1

CASZ1, also known as Castor zinc finger 1, is a transcription factor that plays a crucial role in neural, cardiac, and cardiovascular development. It is involved in regulating cell fate and tissue morphogenesis. CASZ1 functions through its zinc finger domains, which bind to DNA and regulate gene transcription. It is associated with various signaling pathways, including PI3K-AKT-mTOR and MAPK pathways, and is implicated in diseases such as neuroblastoma, cardiovascular disorders, and certain cancers. Research into CASZ1 has led to potential therapeutic targets for diseases like neuroblastoma and cardiovascular diseases, with ongoing drug development research exploring its role in various conditions.

Popular Product:

CASZ1 Antibody (CSB-PA773036LA01HU)

Validated Data

Western Blot
Positive WB detected in: Jurkat whole cell lysate
All lanes: CASZ1 antibody at 4.8μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 191, 125 kDa
Observed band size: 191 kDa

IHC image of CSB-PA773036LA01HU diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

The following CASZ1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CASZ1 Antibodies

CASZ1 Proteins

CASZ1 Antibodies

CASZ1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA773036LA01HU	CASZ1 Antibody	Human	ELISA, WB, IHC

CASZ1 Proteins

CASZ1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP773036HU CSB-EP773036HU CSB-BP773036HU CSB-MP773036HU CSB-EP773036HU-B	Recombinant Human Zinc finger protein castor homolog 1 (CASZ1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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