CD226, CD226 antigen, alias PTA1, DNAM-1, TLiSA1.CD226 is encoded by the human CD226 gene, which is located in the q22.2 region of chromosome 18.The protein encoded by CD226 is a glycoprotein that is a member of the immunoglobulin superfamily, which contains 2 Ig-like domains in the V set.
The mechanism of action of CD226 involves mediating cell adhesion of platelets and megakaryocytes to vascular endothelial cells, as well as playing a role in megakaryocyte maturation. CD226 is expressed on the surface of NK cells, T cells, monocytes, and platelets, and is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity, and cytotoxicity T-cell and natural killer cell-mediated lymphokine secretion.
CD226 is closely associated with the development of autoimmune diseases, infectious diseases and tumors, and is an important molecule in immunological research.
Recombinant Human CD226 antigen (CD226), partial (Active) (CSB-MP618996HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
FACS assay shows that Human CD226 can bind to 293F cell overexpressing human CD155.
CD226 Antibody (CSB-PA618996ESR2HU)
Validated Data
Western blot
All lanes: CD226 antibody at 2.61µg/ml + A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 39 kDa
Observed band size: 39 kDa
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA618996ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA618996ESR2HU at dilution of 1:100
Human CD226 antigen(CD226) ELISA kit (CSB-EL004901HU)
Validated Data
Code: CSB-EL004901HU
Size: 96T,5×96T,10×96T
Sensitivity: 0.22 ng/mL
Detection Range: 0.9 ng/mL-60 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following CD226 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CD226 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004901GA01HU | CD226 Antibody | Human | ELISA,WB |
CSB-PA005645 | CD226 Antibody | Human | WB, ELISA |
CSB-PA006678 | Phospho-CD226 (S329) Antibody | Human,Mouse,Monkey | WB, IHC, IF, ELISA |
CSB-PA006679 | CD226 Antibody | Human,Mouse,Monkey | WB, IHC, IF, ELISA |
CSB-PA968069 | CD226 Antibody | Human | ELISA,IHC |
CSB-PA016936 | CD226 Antibody | Human | ELISA,IHC |
CSB-PA618996ESR2HU | CD226 Antibody | Human | ELISA, WB, IHC |
CD226 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618996HU CSB-EP618996HU CSB-BP618996HU CSB-EP618996HU-B |
Recombinant Human CD226 antigen (CD226), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP618996HU | Recombinant Human CD226 antigen (CD226), partial (Active) | Mammalian cell |
CSB-MP618996HU-B | Recombinant Human CD226 antigen (CD226), partial, Biotinylated | Mammalian cell |
CD226 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP817006MO CSB-EP817006MO CSB-BP817006MO CSB-MP817006MO CSB-EP817006MO-B |
Recombinant Mouse CD226 antigen (Cd226), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD226 Proteins for Macaca mulatta (Rhesus macaque)
Code | Product Name | Source |
---|---|---|
CSB-CF004901MOW | Recombinant Macaca mulatta (Rhesus macaque) CD226 antigen (CD226) | in vitro E.coli expression system |
CSB-YP004901MOW1 CSB-EP004901MOW1 CSB-BP004901MOW1 CSB-MP004901MOW1 CSB-EP004901MOW1-B |
Recombinant Macaca mulatta (Rhesus macaque) CD226 antigen (CD226), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD226 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL004901HU | Human CD226 antigen(CD226) ELISA kit | serum, plasma, tissue homogenates | 0.22 ng/mL |