CLDN7, or tight junction protein 7, is a protein encoded by the CLDN7 gene and part of the tight junction protein family. It is expressed in epithelial and endothelial cells and is involved in forming tight junctions, regulating paracellular permeability and ion selectivity, and maintaining cell polarity and tissue integrity. CLDN7 dysfunction is associated with diseases like inflammatory bowel disease and tumor development, with its expression levels in tumors correlating with invasion and prognosis, marking it as a potential target for cancer therapy.
CLDN7 Monoclonal Antibody (CSB-MA963136)
Validated Data
IHC image of CSB-MA963136 diluted at 1:100 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-mouse IgG polymer labeled by HRP and visualized using 0.05% DAB.
Human Claudin-7(CLDN7) ELISA kit (CSB-EL005509HU)
Validated Data
Code: CSB-EL005509HU
Size: 96T,5×96T,10×96T
Sensitivity: 3.9 pg/mL
Detection Range: 15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following CLDN7 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CLDN7 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA729723 | Phospho-CLDN7 (Tyr210) Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA046041 | CLDN7 (Ab-210) Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA992810 | CLDN7 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA007233 | Phospho-CLDN7 (Y210) Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA007235 | CLDN7 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA007241 | CLDN7 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA092060 | CLDN7 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA119092 | CLDN7 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-MA963136 | CLDN7 Monoclonal Antibody | Human | ELISA, IHC |
CLDN7 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF005509HU | Recombinant Human Claudin-7 (CLDN7) | in vitro E.coli expression system |
CSB-YP005509HU1 CSB-EP005509HU1 CSB-BP005509HU1 CSB-MP005509HU1 CSB-EP005509HU1-B |
Recombinant Human Claudin-7 (CLDN7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CLDN7 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL005509HU | Human Claudin-7(CLDN7) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 3.9 pg/mL |